My Brother, My Brother and Me is a comedy advice show that barely offers any advice (and usually spirals out of control). In each episode, real-life brothers Justin, Travis, and Griffin McElroy pick a question from a viewer and spin it into a ridiculous adventure set in their hometown of Huntington, West Virginia. With cameras in tow, the brothers end up dragging their families, local luminaries, celebrity guests, and supernatural entities into their whirlpool of comedy chaos.