Boris and Doris Anderson live with their oldest son Caillou and his younger siblings Rosie, Cody, Daisy, Emily, and Lily Anderson in their home. Caillou is a well-behaved child who occasionally gets into mischief, but not as frequently as Rosie, Boris and Doris's second oldest daughter. Rosie has a habit of doing things that get her into trouble quickly, resulting in her being grounded by her parents and siblings.