Kamizuru Ryoko, a female detective with a brilliant mind and a mastery of disguise, teams up with Takayama Nobukiho, a man with an IQ of 140, to solve various cases in the most daring ways, defeating the "impossible" enemies through "impossible" methods. At the same time, the duo confront their own past conflicts - Takayama dealing with a conflict with his family, while Kamizuru has no recollection of an incident that led to her disbarment.